Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815874 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL1698794 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL6262083 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2LPAR5LMNAKDM4EDUSP3 | |
| SCHEMBL14803320 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LPAR5LMNAKDM4EDUSP3 | |
| SCHEMBL17715424 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LPAR5LMNAKDM4EDUSP3 | |
| SCHEMBL9962912 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LPAR5LMNAKDM4EDUSP3 | |
| SCHEMBL213379 | 0.76 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNALPAR6LPAR1 | |
| SCHEMBL7340 | 0.76 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNALPAR6LPAR1 | |
| SCHEMBL12284729 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2LPAR5LMNAKDM4EDUSP3 | |
| SCHEMBL14278848 | 0.76 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNALPAR6LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575282-B2 | Compound modified by a phosphoramidate and/or phosphonamide group and use thereof | FREIE UNIVERSITAET BERLIN (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20120065344-A1 | COMPOUND MODIFIED BY A PHOSPHORAMIDATE AND/OR PHOSPHONAMIDE GROUP AND USE THEREOF | FREIE UNIVERSITAET BERLIN (DE) | 2012-03-15 | — | — | US | disclosed |