Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14803320 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2LPAR5GABRR1GABBR2GABBR1 | |
| SCHEMBL17715424 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2LPAR5GABRR1GABBR2GABBR1 | |
| SCHEMBL15625020 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2LPAR5GABRR1GABBR2GABBR1 | |
| SCHEMBL12677435 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2LPAR5GABRR1GABBR2GABBR1 | |
| SCHEMBL14031447 | 0.82 | LPAR5 (0.41) | SMN1; SMN2LPAR5GABRR1GABBR2GABBR1 | |
| SCHEMBL213379 | 0.81 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNAALDH1A1PGK1 | |
| SCHEMBL7340 | 0.81 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNAALDH1A1PGK1 | |
| SCHEMBL14278848 | 0.81 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNAALDH1A1PGK1 | |
| SCHEMBL7341 | 0.81 | PGK1 (0.52) | SMN1; SMN2LPAR5LMNAALDH1A1PGK1 | |
| SCHEMBL30148756 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LPAR5USP2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9545372-B2 | Oral and dental hygiene and cleaning agents for reducing re-staining of teeth | HENKEL AG & CO. KGAA (DE) | 2017-01-17 | — | — | US | disclosed |
| US-20160101035-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING RE-STAINING OF TEETH | HENKEL AG & CO. KGAA (DE) | 2016-04-14 | — | — | US | disclosed |
| US-8501242-B2 | Methods and compositions for treating neoplasia | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2013-08-06 | — | — | US | disclosed |
| US-8252878-B2 | Polymer | BIOCOMPATIBLES UK LIMITED (GB) | 2012-08-28 | — | — | US | disclosed |
| US-20120156212-A1 | METHODS AND COMPOSITIONS FOR TREATING NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION | 2012-06-21 | — | — | US | disclosed |
| US-20090304770-A1 | POLYMER | BIOCOMPATIBLES UK LIMITED (GB) | 2009-12-10 | — | — | US | disclosed |
| US-7160953-B2 | Polymeric surface coatings | BIOCOMPATIBLES UK LIMITED (GB) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101035-A1 | ORAL AND DENTAL HYGIENE AND CLEANING AGENTS FOR REDUCING RE-STAINING OF TEETH | CAT, MPO, DHX35 | SMN1; SMN2 4376/4885LPAR5 3217/4885GABRR1 4367/4885 |
| US-20090304770-A1 | POLYMER | MLX, BMX, PUF60 | SMN1; SMN2 4486/4885LPAR5 4808/4885GABRR1 657/4885 |
| US-20120156212-A1 | METHODS AND COMPOSITIONS FOR TREATING NEOPLASIA | TYMS, UNG, TYMP | SMN1; SMN2 3011/4885LPAR5 3097/4885GABRR1 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.