Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1314080 | 0.93 | ALDH1A1 (0.46) | ALDH1A1CES2CES1TSHRMEN1 | |
| SCHEMBL10332197 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CES2CES1TSHRMEN1 | |
| SCHEMBL103420 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CES2CES1 | |
| SCHEMBL28124102 | 0.82 | HTT (0.39) | ALDH1A1CES2CES1TSHRHSD17B10 | |
| SCHEMBL16122067 | 0.82 | CES2 (0.54) | ALDH1A1CES2CES1 | |
| SCHEMBL11696756 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CES2CES1 | |
| SCHEMBL2295038 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CES2CES1 | |
| SCHEMBL7756813 | 0.80 | CA12 (0.40) | ALDH1A1TSHRMEN1LMNAMAPT | |
| SCHEMBL29272758 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CES2CES1 | |
| SCHEMBL11858927 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096371-A1 | ISOINDOLINONE PIGMENTS AND A METHOD OF MANUFACTURING. | SUDARSHAN CHEMICAL INDUSTRIES LTD. (IN) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096371-A1 | ISOINDOLINONE PIGMENTS AND A METHOD OF MANUFACTURING. | SUDARSHAN CHEMICAL INDUSTRIES LTD. (IN) | 2008-08-14 | — | — | WO | disclosed |
| EP-0895991-B1 | Halogenating agent | MITSUI CHEMICALS INC (JP) | 2008-07-09 | — | — | EP | disclosed |
| CN-101012174-A | Halogenating agents | MITSUI CHEMICALS INC (JP) | 2007-08-08 | — | — | CN | disclosed |
| US-6632949-B2 | Difluoro-diamine methylene derivatives | MITSUI CHEMICALS, INC. (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20030004348-A1 | Halogenating agents | SONODA HIROSHI (JP) | 2003-01-02 | — | — | US | disclosed |
| US-6458990-B1 | BIS(DIHYDROCARBYLAMINO)DIFLUOROMETHANE OR CYCLIC DERIVATIVES THEREOF; FORMING BY REACTING ALKALI METAL HALIDE WITH THE CORRESPONDING AMIDINIUM SALT; FLUORINATION OF ALCOHOLS, THIOPHENOLS, ALDEHYDES, AND KETONES | MITSUI CHEMICALS, INC. (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-0741123-B1 | Process for the preparation of salts of substituted or unsubstituted phthalic acid derivatives | CLARIANT GMBH (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | SONODA HIROSHI (JP) | 2002-04-11 | — | — | US | disclosed |
| US-6329529-B1 | FOR FLUORINATING OF ORGANIC COMPOUNDS, EFFICIENCY, POLLUTION CONTROL | MITSUI CHEMICALS, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0112927-B1 | RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-02-11 | — | — | EP | disclosed |
| US-4522993-A | COPOLYMER HAVING UNITS FROM A BIS-ALLYL HALOGENATED BENZENE DICARBOXYLATE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1985-06-11 | — | — | US | disclosed |
| EP-0140482-A2 | Fluorination process for the production of nuclear fluorinated phthaloyl- and terephthaloyl fluorides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-05-08 | — | — | EP | disclosed |
| EP-0112927-A1 | RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-07-11 | — | — | EP | disclosed |
| EP-0061013-B1 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES | BAYER AG (DE) | 1984-06-27 | — | — | EP | disclosed |
| EP-0031436-B1 | A METHOD FOR THE CLEAVAGE OF SILOXANES | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1984-02-15 | — | — | EP | disclosed |
| US-4388246-A | THERMAL SPLITTING OF CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-06-14 | — | — | US | disclosed |
| EP-0061013-A1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4310680-A | METAL OR METAL COMPOUND CATALYST | DYNAMIT NOBEL AG (DE) | 1982-01-12 | — | — | US | disclosed |
| EP-0031436-A2 | A method for the cleavage of siloxanes | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004348-A1 | Halogenating agents | AFF1, NAF1, AFF2 | ALDH1A1 833/4885CES2 1384/4885CES1 840/4885 |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | AFF1, NAF1, CYP2F1 | ALDH1A1 1492/4885CES2 1835/4885CES1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.