Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602312 | 0.90 | NPC1 (0.43) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4889304 | 0.88 | NPC1 (0.45) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4602758 | 0.88 | NPC1 (0.45) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4886956 | 0.81 | NPC1 (0.43) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4602310 | 0.81 | NPC1 (0.43) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4603832 | 0.80 | TSHR (0.39) | NPC1RAB9AEPHX2TSHRALDH1A1 | |
| SCHEMBL4887977 | 0.73 | TSHR (0.41) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4887987 | 0.73 | TSHR (0.41) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4617340 | 0.72 | NPC1 (0.45) | NPC1RAB9AEPHX2HRH2HRH1 | |
| SCHEMBL4603007 | 0.71 | NPC1 (0.41) | NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915342-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2006115353-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2006-11-02 | — | — | WO | disclosed |