Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | Q9HBH1 | 1/20 | 0.36 | |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887977 | 1.00 | TSHR (0.41) | TSHRNPC1RAB9AADAM17HRH2 | |
| SCHEMBL4886956 | 0.91 | NPC1 (0.43) | TSHRNPC1RAB9AHRH2HRH1 | |
| SCHEMBL4602310 | 0.91 | NPC1 (0.43) | TSHRNPC1RAB9AHRH2HRH1 | |
| SCHEMBL4886058 | 0.90 | KMT2A (0.43) | TSHRNPSR1MEN1KMT2A | |
| SCHEMBL4886049 | 0.90 | KMT2A (0.43) | TSHRNPSR1MEN1KMT2A | |
| SCHEMBL4602951 | 0.89 | NPSR1 (0.48) | TSHRADAM17NPSR1MEN1KMT2A | |
| SCHEMBL4877576 | 0.89 | NPSR1 (0.48) | TSHRADAM17NPSR1MEN1KMT2A | |
| SCHEMBL14066497 | 0.89 | TSHR (0.44) | TSHRNPSR1MEN1KMT2AEPHX2 | |
| SCHEMBL4618893 | 0.85 | MMP2 (0.48) | TSHRNPC1RAB9AADAM17MMP1 | |
| SCHEMBL4889304 | 0.82 | NPC1 (0.45) | TSHRNPC1RAB9AHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234333-A1 | Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof | KANG JAE-HOON | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234333-A1 | Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof | PDF, PEPD, DHPS | TSHR 3586/4885NPC1 2506/4885RAB9A 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.