Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602312 | 0.90 | NPC1 (0.43) | TSHRALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL4603826 | 0.86 | TSHR (0.39) | TSHRALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL4902899 | 0.86 | TSHR (0.39) | TSHRALDH1A1LMNASMN1; SMN2HDAC3 | |
| SCHEMBL4602765 | 0.80 | NPC1 (0.43) | TSHRALDH1A1TP53NPSR1EPHX2 | |
| SCHEMBL4603007 | 0.79 | NPC1 (0.41) | TSHRLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4884110 | 0.78 | KMT2A (0.41) | TSHRMEN1KMT2AMCHR1NPC1 | |
| SCHEMBL4884080 | 0.78 | KMT2A (0.41) | TSHRMEN1KMT2AMCHR1NPC1 | |
| SCHEMBL4602474 | 0.78 | MMP1 (0.44) | MEN1KMT2ANPSR1 | |
| SCHEMBL4603077 | 0.78 | TSHR (0.41) | TSHRMEN1KMT2AEPHX2MCHR1 | |
| SCHEMBL4883080 | 0.78 | TSHR (0.41) | TSHRMEN1KMT2AEPHX2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915342-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2006115353-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2006-11-02 | — | — | WO | disclosed |