Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076165 | 0.84 | TSPO (0.47) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL2088431 | 0.84 | POLQ (0.46) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL2088432 | 0.84 | POLQ (0.50) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL5476758 | 0.82 | POLQ (0.45) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL20560739 | 0.81 | LMNA (0.42) | POLQESR1GAALMNANFKB1 | |
| SCHEMBL31222332 | 0.81 | TACR1 (0.46) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL11309832 | 0.79 | POLQ (0.50) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL13041529 | 0.79 | POLQ (0.50) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL2754139 | 0.79 | POLQ (0.43) | POLQHDAC6ESR1GAALMNA | |
| SCHEMBL28595013 | 0.79 | LMNA (0.40) | POLQESR1GAALMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940783-A1 | PROCESS FOR PREPARING N, N-SUBSTITUTED CARBAMOYL HALIDES | GLAXO GROUP LIMITED (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007048642-A1 | PROCESS FOR PREPARING N, N-SUBSTITUTED CARBAMOYL HALIDES | GLAXO GROUP LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
| US-5767286-A | REACTING A TETRAZOLINONE WITH A CARBAMOYL CHLORIDE IN THE PRESENCE OF 4-DIMETHYLAMINOPYRIDINE | NIHON BAYER AGROCHEM K. K. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0646577-B1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | BAYER AGROCHEM KK (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0646577-A1 | Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5312820-A | Angiotensin antagonist for treatment of hypertension | MERCK & CO., INC. (US) | 1994-05-17 | — | — | US | disclosed |