Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873970 | 0.92 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL3884082 | 0.78 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL3873751 | 0.75 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL4960875 | 0.73 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL3872809 | 0.72 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL3872191 | 0.70 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL3425230 | 0.70 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL2161550 | 0.70 | ABCG2 (0.41) | AGTR1POLBSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL30743612 | 0.69 | ABCG2 (0.55) | AGTR1POLBSMN1; SMN2ABCG2 | |
| SCHEMBL3407499 | 0.69 | AGTR1 (0.61) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899328-A1 | A PROCESS FOR THE PREPARATION OF LOSARTAN DERIVATIVES BY CHLORINATION AND REDUCTION OF THE RESPECTIVE 1H-IMIDAZOLE-5-CARBALDEHYDES | KRKA, D.D., Novo Mesto (SI) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003280-A1 | A PROCESS FOR THE PREPARATION OF LOSARTAN DERIVATIVES BY CHLORINATION AND REDUCTION OF THE RESPECTIVE 1H-IMIDAZOLE-5-CARBALDEHYDES | KRKA, D.D. NOVO MESTO (SI) | 2007-01-11 | — | — | WO | disclosed |