Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313646 | 0.99 | MAOA (0.46) | MAOAMAOBACSL1ALOX5MEN1 | |
| SCHEMBL16563060 | 0.97 | MAOA (0.44) | MAOAMAOBACSL1ALOX5MEN1 | |
| SCHEMBL2804823 | 0.89 | MAOA (0.42) | MAOAMAOBACSL1ALOX5PTGS1 | |
| SCHEMBL152831 | 0.87 | MAOA (0.43) | MAOAMAOBACSL1MEN1KMT2A | |
| Potassium Ion SCHEMBL10812686 | 0.87 | MAOA (0.36) | MAOAMAOBACSL1L3MBTL1MAPKAPK2 | |
| SCHEMBL135629 | 0.87 | BID (0.43) | MAOAMAOBKDM4E | |
| SCHEMBL7515697 | 0.86 | MAOA (0.42) | MAOAMAOBACSL1MEN1KMT2A | |
| SCHEMBL9340083 | 0.86 | MAOA (0.42) | MAOAMAOBACSL1MEN1KMT2A | |
| SCHEMBL672014 | 0.86 | MAOA (0.42) | MAOAMAOBACSL1MEN1KMT2A | |
| SCHEMBL16414620 | 0.86 | MAOA (0.42) | MAOAMAOBACSL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940777-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | Sanofi-Aventis (FR) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007034253-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |