SCHEMBL4603049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14159167	0.93	MAPT (0.47)	PPARGITGB2ICAM1ITGAL
	SCHEMBL14557644	0.91	MAPT (0.48)	PPARGITGB2ICAM1ITGAL
	SCHEMBL14557737	0.91	AKT1 (0.44)	SNCAECE1AKT1
	SCHEMBL14557645	0.90	TACR1 (0.46)	ECE1
	SCHEMBL14557917	0.90	HPGDS (0.45)	PPARG
	SCHEMBL14564912	0.90	HDAC3 (0.46)	PPARGAKT1ITGB2ICAM1ITGAL
	SCHEMBL14557638	0.90	CDK4 (0.50)	ITGB2ICAM1ITGAL
	SCHEMBL4600803	0.90	HDAC3 (0.46)	PPARGAKT1ITGB2ICAM1ITGAL
	SCHEMBL14557741	0.89	HPGDS (0.46)	PPARG
	SCHEMBL14557900	0.89	CCKBR (0.44)	ROCK2PRKACAGSK3BPRKXROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.