Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438206 | 0.86 | MME (0.57) | CYP1A2MMENPSR1FPR2NAALAD2 | |
| SCHEMBL7890615 | 0.86 | MME (0.57) | CYP1A2MMENPSR1FPR2NAALAD2 | |
| SCHEMBL436655 | 0.86 | MME (0.57) | CYP1A2MMENPSR1FPR2NAALAD2 | |
| SCHEMBL438205 | 0.86 | MME (0.57) | CYP1A2MMENPSR1FPR2NAALAD2 | |
| SCHEMBL26993397 | 0.83 | EPHX1 (0.53) | CYP1A2MMENPSR1ALPIPKM | |
| SCHEMBL15866448 | 0.83 | TAAR1 (0.50) | CYP1A2MMENPSR1NPC1RAB9A | |
| SCHEMBL29422128 | 0.81 | KMT2A (0.43) | FPR2MMP2 | |
| SCHEMBL22340052 | 0.81 | CYP3A4 (0.41) | CYP1A2MMP2MMP9 | |
| SCHEMBL29310627 | 0.81 | CYP1A2 (0.46) | CYP1A2MMENPSR1NPC1RAB9A | |
| SCHEMBL21724950 | 0.80 | ATM (0.61) | RAB9AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915149-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AEterna Zentaris GmbH (DE) | 2008-04-30 | — | — | EP | claimed |
| WO-2007020013-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2007-02-22 | — | — | WO | claimed |