SCHEMBL438206

SCHEMBL438206

O=C(O)[C@H](Cc1ccccc1)NI

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 2/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.56
▸ CYP1A2 P05177 1/20 0.55
▸ NAALAD2 Q9Y3Q0 2/20 0.54
▸ FPR2 P25090 3/20 0.54
▸ FOLH1 Q04609 1/20 0.53
▸ MMP2 P08253 4/20 0.53
▸ MMP9 P14780 3/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ ADAMTS4 O75173 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7890615 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL436655 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL438205 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL4603054 0.86 CYP1A2 (0.48) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL55971 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL26993397 0.85 EPHX1 (0.53) MMENPSR1CYP1A2MMP2L3MBTL1
SCHEMBL55972 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL8745399 0.85 FPR2 (0.55) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL3105902 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL9068541 0.83 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 — — US claimed
WO-2024163598-A2 PEPTIDES COMPRISING THIOESTER GROUPS, INCLUDING DEPSIPEPTIDE THIOESTERS, METHODS OF MAKING, AND USE THEREOF BRANDEIS UNIVERSITY (US) 2024-08-08 — — WO claimed
CN-118344390-A Polyboronate substituted phenylalanine derivative and preparation method and application thereof 莆田兰海核医学研究中心 2024-07-16 — — CN claimed
EP-4347799-A1 MICROORGANISMS AND USES THEREOF United Kingdom Research and Innovation (GB) 2024-04-10 — — EP claimed
EP-4161581-A1 BISPECIFIC ANTIBODY-DRUG CONJUGATES TARGETING EGFR AND MUC1 AND USES THEREOF Merck Patent GmbH (DE) 2023-04-12 — — EP claimed
EP-4139340-A1 HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA GAMMAC DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER Merck Sharp & Dohme LLC (US) 2023-03-01 — — EP claimed
WO-2022248061-A1 MICROORGANISMS AND USES THEREOF UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2022-12-01 — — WO claimed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 — — CN claimed
EP-3923991-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES Ambrx, Inc. (US) 2021-12-22 — — EP claimed
WO-2021216478-A1 HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA GAMMAc DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER MERCK SHARP & DOHME CORP. (US) 2021-10-28 — — WO claimed
CN-101238143-A Incorporation of non-naturally encoded amino acids into proteins AMBRX INC (US) 2008-08-06 — — CN claimed
CN-101223272-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST (US) 2008-07-16 — — CN claimed
WO-2008073184-A2 GENETIC INCORPORATION OF UNNATURAL AMINO ACIDS INTO PROTEINS IN MAMMALIAN CELLS THE SCRIPPS RESEARCH INSTITUTE (US) 2008-06-19 — — WO claimed
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 — — US claimed
WO-2007079953-A2 IN VITRO METHOD TO PREDICT THE TUMOR SENSITIVITY TO PHARMACOTHERAPY AND ENDORADIOTHERAPY SAMNICK SAMUEL (DE) 2007-07-19 — — WO claimed
US-20070128108-A1 Therapy of malignant neoplasias SAMNICK SAMUEL 2007-06-07 — — US claimed
WO-2007060012-A2 USE OF L-PHENYLALANINE CONJUGATED TO AN EMITTING ISOTOPE FOR THERAPY OF HORMONE DEPENDENT CARCINOMA SAMNICK SAMUEL (DE) 2007-05-31 — — WO claimed
US-20010018042-A1 Attaching a biocompatible lipid avid agent to a lipid accumulation in a wall of the artery; predicting rupture; atherosclerosis diagnosis MEDIVAS, L.L.C. 2001-08-30 — — US claimed
US-6232305-B1 ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS NAEJA PHARMACEUTICAL INC. (CA) 2001-05-15 — — US claimed
WO-2000033891-A1 METHODS FOR DETECTION OF VULNERABLE PLAQUES USING A DETECTABLE LIPID-AVID AGENT MEDIVAS, LLC (US) 2000-06-15 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070128108-A1 Therapy of malignant neoplasias VHL, PAH, FAP MME 391/4885NPSR1 1272/4885CYP1A2 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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