SCHEMBL436655

SCHEMBL436655

O=C(O)[C@H](Cc1ccccc1)NI.O=C(O)[C@H](Cc1ccccc1)NI

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 2/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.56
▸ CYP1A2 P05177 1/20 0.55
▸ NAALAD2 Q9Y3Q0 2/20 0.54
▸ FPR2 P25090 3/20 0.54
▸ FOLH1 Q04609 1/20 0.53
▸ MMP2 P08253 4/20 0.53
▸ MMP9 P14780 3/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ ADAMTS4 O75173 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438206 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL7890615 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL438205 1.00 MME (0.57) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL4603054 0.86 CYP1A2 (0.48) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL55971 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL26993397 0.85 EPHX1 (0.53) MMENPSR1CYP1A2MMP2L3MBTL1
SCHEMBL55972 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL8745399 0.85 FPR2 (0.55) MMENPSR1CYP1A2NAALAD2FPR2
SCHEMBL3105902 0.85 FOLH1 (0.56) MMENAALAD2FOLH1L3MBTL1
SCHEMBL9068541 0.83 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781310-B1 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME UNIV RAMOT (IL) 2015-10-14 — — EP claimed
US-8927689-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-01-06 — — US claimed
US-8796023-B2 Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-08-05 — — US claimed
US-20120063276-A1 PEPTIDE NANOSTRUCTURES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2012-03-15 — — US claimed
US-8017586-B2 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-09-13 — — US claimed
US-7786086-B2 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2010-08-31 — — US claimed
EP-1781310-A4 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME UNIV RAMOT (IL) 2009-07-08 — — EP claimed
US-20090123553-A1 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-05-14 — — US claimed
US-20090121709-A1 Peptide nanostructures encapsulating A foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-05-14 — — US claimed
US-7504383-B2 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-03-17 — — US claimed
US-7491699-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. 2009-02-17 — — US claimed
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2008-01-10 — — US claimed
EP-1781310-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME Ramot at Tel Aviv University Ltd. (IL) 2007-05-09 — — EP claimed
US-20060079455-A1 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 — — US claimed
US-20060079454-A1 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 — — US claimed
WO-2006027780-A2 PEPTIDE NANOSTRUCTURES CONTAINING END-CAPPING MODIFIED PEPTIDES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-03-16 — — WO claimed
WO-2006013552-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-02-09 — — WO claimed
US-20240167062-A1 HYDROGEL SYSTEM FOR CONTROLLING OXYGEN CONCENTRATION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-05-23 — — US disclosed
WO-2006027780-A2 PEPTIDE NANOSTRUCTURES CONTAINING END-CAPPING MODIFIED PEPTIDES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-03-16 — — WO disclosed
WO-2006013552-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-02-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240167062-A1 HYDROGEL SYSTEM FOR CONTROLLING OXYGEN CONCENTRATION HIF1A, HAO2, EGLN2 MME 3813/4885NPSR1 600/4885CYP1A2 1425/4885
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody DNPEP, LNPEP, ANPEP MME 138/4885NPSR1 2419/4885CYP1A2 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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