Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572828 | 0.91 | TGFBR1 (0.56) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13166155 | 0.91 | TGFBR1 (0.56) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4617947 | 0.89 | TGFBR1 (0.74) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4604003 | 0.88 | MEN1 (0.50) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14141142 | 0.87 | MAPT (0.62) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4603429 | 0.87 | MAPT (0.62) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14141064 | 0.86 | MEN1 (0.55) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4606103 | 0.86 | MEN1 (0.55) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4604313 | 0.85 | MEN1 (0.63) | TGFBR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4603171 | 0.84 | MEN1 (0.52) | TGFBR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753512-B1 | TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | claimed |