Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220288 | 0.97 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL424597 | 0.95 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL5080728 | 0.95 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL4447906 | 0.93 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL996122 | 0.93 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11030313 | 0.93 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Propene SCHEMBL28175468 | 0.90 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL25235967 | 0.90 | TSHR (0.56) | TSHRHPGDALDH1A1THRBHSD17B10 | |
| SCHEMBL37108 | 0.90 | TSHR (0.56) | TSHRHPGDALDH1A1THRBHSD17B10 | |
| SCHEMBL93561 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915384-A1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | Dow Corning Toray Co., Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007020932-A1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | DOW CORNING TORAY CO., LTD. (JP) | 2007-02-22 | — | — | WO | disclosed |