Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424597 | 0.93 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL5080728 | 0.93 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL4603161 | 0.93 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL1024880 | 0.93 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL5191072 | 0.91 | TSHR (0.47) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL11030313 | 0.91 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL11220288 | 0.90 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL8901734 | 0.89 | TSHR (0.45) | TSHRALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL4447906 | 0.86 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL4361747 | 0.85 | TSHR (0.49) | TSHRALDH1A1THRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445980-B1 | METHOD OF BONDING A FLUOROPOLYMER USING A SILANE CONTAINING BONDING PROMOTER | 3M INNOVATIVE PROPERTIES CO (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2011005443-A2 | METHOD OF BONDING A FLUOROPOLYMER USING A SILANE CONTAINING BONDING PROMOTER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |
| US-20070299214-A1 | trimethoxysilyl-group-terminated polyoxypropylene polymer containing a reactive silicon group, and being crosslinkable through the formation of a siloxane bonding; neodecanoic acid or tin carbonate as curing catalyst; adhesion-imparting agent aminopropyltrimethoxysilane; one-component sealant, adhesives | KANEKA CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |