SCHEMBL4603384

SCHEMBL4603384

Cc1ccc(N(CCCCO)CCCCO)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CNR2 P34972 2/20 0.38
RAB9A P51151 1/20 0.37
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
ACHE P22303 1/20 0.33
MAPK1 P28482 1/20 0.33
MLYCD O95822 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147288 0.98 CYP2C19 (0.41) CYP2C19ALDH1A1TSHRKDM4ETDP1
SCHEMBL146243 0.94 CYP2C19 (0.44) CYP2C19ALDH1A1TSHRKDM4ETDP1
SCHEMBL25913652 0.93 CNR2 (0.44) CYP2C19ALDH1A1TSHRKDM4ECNR2
SCHEMBL33921 0.85 CYP2C19 (0.47) CYP2C19ALDH1A1TSHRKDM4ETDP1
SCHEMBL15714440 0.84 CNR2 (0.43) CYP2C19ALDH1A1TSHRKDM4ETDP1
SCHEMBL12237637 0.83 KMT2A (0.41) ALDH1A1TSHRTDP1CNR2RAB9A
SCHEMBL4358315 0.82 EGFR (0.43) CYP2C19ALDH1A1KDM4ETDP1CNR2
SCHEMBL2782797 0.82 ALDH1A1 (0.36) ALDH1A1TSHRKDM4ETDP1CNR2
SCHEMBL14303779 0.82 ALDH1A1 (0.43) ALDH1A1TSHRKDM4ETDP1RAB9A
SCHEMBL11313427 0.81 CNR2 (0.49) CYP2C19ALDH1A1TSHRCNR2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872529-B2 BINDER FOR BUILDING STRUCTURES ASAHI CHEMICAL IND (JP) 2008-07-09 EP disclosed
EP-0872529-B1 BINDER FOR BUILDING STRUCTURES ASAHI CHEMICAL IND (JP) 2004-09-29 EP disclosed
US-6015845-A Binder for building structure ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-01-18 US disclosed
EP-0872529-A1 BINDER FOR BUILDING STRUCTURES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-10-21 EP disclosed