Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1577827 | 0.91 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methyl Alcohol SCHEMBL28080029 | 0.91 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL31267242 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19273 | 0.91 | — | — | |
| SCHEMBL5167665 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL316282 | 0.90 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acetamide SCHEMBL27967080 | 0.89 | MAPT (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4787125 | 0.89 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL28462478 | 0.88 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL28424741 | 0.88 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005886-A1 | THERMALLY PROTECTIVE INTUMESCENT COMPOSITIONS | W.R. GRACE & CO.-CONN. (US) | 2001-01-25 | — | — | WO | claimed |
| EP-0617715-B1 | UTILIZATION OF AQUEOUS BINDER COMPOSITIONS FOR THE LAMINATION OF CELLULOSE-TISSUE | WACKER CHEMIE GMBH (DE) | 1996-04-17 | — | — | EP | claimed |
| US-5508100-A | BINDING TWO OR MORE LAYERS OF CELLULAR PULP OR CELLULOSE FIBER TISSUES BY APPLYING BINDER CONSISTING OF PLASTIC DISPERSION BASED ON COPOLYMER OR TERPOLYMER, FILLERS, THICKENERS, DISPERSING AGENTS; AFFIXING AND DRYING | WACKER-CHEMIE GMBH (DE) | 1996-04-16 | — | — | US | claimed |
| US-4746565-A | SELF-EXTINGUISHING, THERMOPLASTIC FACINGS FABRICS | UNITED MERCHANTS AND MANUFACTURERS, INC. (US) | 1988-05-24 | — | — | US | claimed |
| EP-0261841-A2 | Improved fire barrier fabrics | SPRINGS INDUSTRIES INC. (US) | 1988-03-30 | — | — | EP | claimed |
| US-4690859-A | COATED FIBER GLASS; ELIMINATES SELF-ABRASION | UNITED MERCHANTS & MANUFACTURERS INC. (US) | 1987-09-01 | — | — | US | claimed |
| WO-2024038177-A1 | BITUMEN/POLYMER COMPOSITION WITH IMPROVED MECHANICAL PROPERTIES | TOTALENERGIES ONETECH (FR) | 2024-02-22 | — | — | WO | disclosed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | disclosed |
| EP-4247791-A2 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-111343963-B | Use of physiologically cooling active ingredients and compositions comprising such active ingredients | 巴斯夫欧洲公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116685575-A | Novel cooling substances and formulations containing these cooling substances | 西姆莱斯股份公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-111053775-B | Physiologically cool active ingredient and use of substances containing such active ingredient | 西姆莱斯股份公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023143741-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | SYMRISE AG (DE) | 2023-08-03 | — | — | WO | disclosed |
| US-4690859-A | COATED FIBER GLASS; ELIMINATES SELF-ABRASION | UNITED MERCHANTS & MANUFACTURERS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0201204-A2 | Fire barrier fabrics | SPRINGS INDUSTRIES INC. (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4609704-A | WET PICK STRENGTH | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4599378-A | DICYCLOPENTADIENYL ACRYLATE OR METHACRYLATE AS CROSSLINKER | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0172354-A1 | Vinyl ester/ethylene copolymer emulsions for paper coating compositions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0167902-A1 | Vinyl acetate copolymer emulsions for paper coating compositions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-01-15 | — | — | EP | disclosed |
| US-4503185-A | DRY PICK AND WET PICK STRENGTHS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | TSHR 1885/4885HPGD 1155/4885ALDH1A1 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.