Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605497 | 0.90 | ALDH1A1 (0.46) | ALDH1A1RECQLSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4606032 | 0.89 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL4605269 | 0.85 | ALDH1A1 (0.47) | ALDH1A1RECQLSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL4605187 | 0.78 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4605904 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4604735 | 0.78 | L3MBTL1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4605838 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4605887 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4617063 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1MEN1 | |
| SCHEMBL4605316 | 0.75 | AKR1C3 (0.46) | ALDH1A1SMN1; SMN2CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720825-B1 | ANTHRANILIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USE AS DHODH INHIBITORS | ACTIVE BIOTECH AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1720825-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | Active Biotech AB (SE) | 2006-11-15 | — | — | EP | disclosed |
| US-7074831-B2 | Compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2006-07-11 | — | — | US | disclosed |
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | ACTIVE BIOTECH AB (SE) | 2005-08-25 | — | — | US | disclosed |
| WO-2005075410-A1 | NEW COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187297-A1 | New compounds, methods for their preparation and use thereof | MALT1, TPMT, FUCA1 | ALDH1A1 308/4885RECQL 2485/4885SMN1; SMN2 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.