Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798662 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDLMNAALPG | |
| SCHEMBL9184870 | 0.72 | KDM4E (0.47) | KDM4EHPRT1ALDH1A1HSD17B10CYP2A6 | |
| Hydrochloric Acid SCHEMBL460640 | 0.71 | KDM4E (0.42) | KDM4EHPRT1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL31614554 | 0.68 | RAD52 (0.54) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL16736485 | 0.68 | RAD52 (0.54) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phenanthrene SCHEMBL2963532 | 0.65 | ALDH1A1 (0.71) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Chrysene SCHEMBL18627967 | 0.65 | HPRT1 (0.93) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Chrysene SCHEMBL1460501 | 0.65 | HPRT1 (0.93) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phenanthrene SCHEMBL6281749 | 0.65 | CYP2A6 (0.92) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phenanthrene SCHEMBL2087874 | 0.65 | CYP2A6 (0.92) | HPRT1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | KDM4E 536/4885HPRT1 300/4885ALDH1A1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.