Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602234 | 0.96 | KDM4E (0.45) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4602096 | 0.92 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4603936 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4604665 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL11711686 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4605222 | 0.84 | HPGD (0.41) | ALDH1A1RAB9AL3MBTL1HPGDCNR2 | |
| SCHEMBL4604028 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4603554 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4249996 | 0.82 | MAPK1 (0.53) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL4603892 | 0.82 | HPGD (0.41) | ALDH1A1RAB9AMAPK1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |