Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | CNR1 | P21554 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602830 | 0.98 | HPGD (0.44) | HPGDRAB9ASMN1; SMN2NPC1CNR2 | |
| SCHEMBL4603371 | 0.96 | HPGD (0.42) | HPGDRAB9ASMN1; SMN2NPC1CNR2 | |
| SCHEMBL4602096 | 0.89 | ALDH1A1 (0.46) | HPGDRAB9ASMN1; SMN2CNR2CNR1 | |
| SCHEMBL4603936 | 0.87 | ALDH1A1 (0.49) | HPGDRAB9ASMN1; SMN2CNR2CNR1 | |
| SCHEMBL4603541 | 0.82 | ALDH1A1 (0.48) | HPGDRAB9ASMN1; SMN2CNR2CNR1 | |
| SCHEMBL4602587 | 0.82 | HPGD (0.42) | HPGDRAB9ANPC1CNR2CNR1 | |
| SCHEMBL4603506 | 0.80 | HPGD (0.45) | HPGDRAB9ASMN1; SMN2NPC1CNR2 | |
| SCHEMBL4244964 | 0.79 | MEN1 (0.43) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL4602234 | 0.77 | KDM4E (0.45) | RAB9ASMN1; SMN2CNR2CNR1MAPK1 | |
| SCHEMBL4248764 | 0.77 | MEN1 (0.46) | HPGDRAB9ASMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |