SCHEMBL460361

SCHEMBL460361

C=CCN(CCCCC)c1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.47
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
PSMD14 O00487 1/20 0.47
TSHR P16473 1/20 0.47
RECQL P46063 1/20 0.47
GFER P55789 1/20 0.47
MAPT P10636 3/20 0.40
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
CNR2 P34972 3/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6843923 0.92 CNR2 (0.37) ALDH1A1TSHRCNR2RXRARXRB
SCHEMBL1825440 0.90 CHKA (0.38) TSHRCNR2RXRARXRBRXRG
SCHEMBL11218745 0.88 ALDH1A1 (0.52) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL6694379 0.87 BDKRB2 (0.35) CNR2RXRARXRBRXRGCHRM2
SCHEMBL45791 0.84 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL8520351 0.83 NPC1 (0.42) TSHRCNR2RXRARXRBRXRG
SCHEMBL3691300 0.83 ALDH1A1 (0.57) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL7771003 0.83 ALDH1A1 (0.57) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL1498858 0.83 ALDH1A1 (0.57) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1
SCHEMBL6263019 0.83 ALDH1A1 (0.57) CYP3A4ALDH1A1TDP1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230416471-A1 VULCANIZATION COMPOSITION FOR REDUCING ALLERGENIC POTENTIAL AND ELASTOMERIC ARTICLES FORMED THEREWITH ALLEGIANCE CORPORATION 2023-12-28 US disclosed
US-11780972-B2 Vulcanization composition for reducing allergenic potential and elastomeric articles formed therewith ALLEGIANCE CORPORATION (US) 2023-10-10 US disclosed
EP-4233771-A2 VULCANIZATION COMPOSITION HAVING REDUCED ALLERGENIC POTENTIAL Allegiance Corporation (US) 2023-08-30 EP disclosed
EP-2585289-B1 VULCANIZATION COMPOSITION HAVING REDUCED ALLERGENIC POTENTIAL ALLEGIANCE CORP (US) 2023-06-07 EP disclosed
US-11242435-B2 Vulcanization composition for reducing allergenic potential and elastomeric articles formed therewith ALLEGIANCE CORPORATION (US) 2022-02-08 US disclosed
US-11214682-B2 Heat stabilized polyamide composition DSM IP ASSETS B.V. (NL) 2022-01-04 US disclosed
CN-110283260-B Methods for recovering rubber from aged briquettes and aged briquettes comprising plant matter from non-hevea plants 株式会社普利司通 2021-09-28 CN disclosed
US-11028188-B2 Processes for recovering rubber from aged briquettes BRIDGESTONE CORPORATION (JP) 2021-06-08 US disclosed
CN-107585344-B Method for packaging and sterilizing elastic articles and packaged elastic articles obtained thereby 忠诚股份有限公司 2021-02-12 CN disclosed
EP-3212608-B1 OXIDATIVE ESTERIFICATION PROCESS FOR MAKING METHYL METHACRYLATE ROHM & HAAS (US) 2020-12-30 EP disclosed
US-6397910-B1 ADHESIVE IS FREE OF VOLATILE ORGANIC COMPOUNDS, PARTICULARLY VOLATILE ORGANIC SOLVENTS. THE GOODYEAR TIRE & RUBBER COMPANY 2002-06-04 US disclosed
EP-1077228-A1 Pneumatic tire having a rubber component containing a liquid polysulfide compound THE GOODYEAR TIRE & RUBBER COMPANY (US) 2001-02-21 EP disclosed
US-5574118-A PHENOL OR THIOPHENOL SUBSTITUTED NORBORNENE MONOMER DSM COPOLYMER, INC. (US) 1996-11-12 US disclosed
EP-0466263-B1 Polymerizable antioxidant and olefin polymers containing bound antioxidant DSM NV (NL) 1996-09-25 EP disclosed
EP-0695733-A1 Olefin polymers containing bound antioxidant DSM N.V. (NL) 1996-02-07 EP disclosed
US-5157164-A Diphenolic or thiophenolic norbornene compounds; Ziegler catalyst COPOLYMER RUBBER & CHEMICAL CORP. (US) 1992-10-20 US disclosed
EP-0466263-A2 Polymerizable antioxidant and olefin polymers containing bound antioxidant DSM N.V. (NL) 1992-01-15 EP disclosed
US-5017727-A Norbornene derivatives COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1991-05-21 US disclosed
EP-0100793-B1 AQUEOUS DISPERSIONS COMPRISING COLLOIDAL SIZED PARTICLES OF A POLYMER AND AN ADDITIVE AND A METHOD FOR THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1986-10-15 EP disclosed
EP-0100793-A1 Aqueous dispersions comprising colloidal sized particles of a polymer and an additive and a method for their preparation THE DOW CHEMICAL COMPANY (US) 1984-02-22 EP disclosed