Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587984 | 1.00 | NOD1 (0.41) | NOD1GLP1RGLO1PTGS1GSTK1 | |
| SCHEMBL4587684 | 0.94 | NOD1 (0.46) | NOD1GLP1RGLO1PTGS1GSTK1 | |
| SCHEMBL4589185 | 0.94 | NOD1 (0.46) | NOD1GLP1RGLO1PTGS1GSTK1 | |
| SCHEMBL4587271 | 0.89 | NOD1 (0.38) | NOD1GLP1RTLR2 | |
| SCHEMBL4587768 | 0.89 | NOD1 (0.39) | NOD1PTGS1TLR2 | |
| SCHEMBL4588699 | 0.89 | NOD1 (0.39) | NOD1PTGS1TLR2 | |
| SCHEMBL4587325 | 0.86 | NOD1 (0.39) | NOD1PTGS1GSTK1 | |
| SCHEMBL4588742 | 0.86 | NOD1 (0.39) | NOD1PTGS1GSTK1 | |
| SCHEMBL4587262 | 0.85 | FOLH1 (0.36) | GLP1RTLR2 | |
| SCHEMBL4587729 | 0.83 | NOD1 (0.43) | NOD1PTGS1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692107-A4 | NITRIC OXIDE RELEASING PYRUVATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1692107-A2 | NITRIC OXIDE RELEASING PYRUVATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005060603-A2 | NITRIC OXIDE RELEASING PYRUVATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2005-07-07 | — | — | WO | disclosed |