Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 3/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587262 | 0.89 | FOLH1 (0.36) | FOLH1SIRT5SIRT6SIRT1TLR2 | |
| SCHEMBL4587984 | 0.89 | NOD1 (0.41) | NOD1TLR2GLP1R | |
| SCHEMBL4603752 | 0.89 | NOD1 (0.41) | NOD1TLR2GLP1R | |
| SCHEMBL4589185 | 0.86 | NOD1 (0.46) | NOD1GLP1R | |
| SCHEMBL4587684 | 0.86 | NOD1 (0.46) | NOD1GLP1R | |
| SCHEMBL4587689 | 0.85 | FOLH1 (0.38) | FOLH1SIRT5SIRT6SIRT1TLR2 | |
| SCHEMBL4588699 | 0.77 | NOD1 (0.39) | NOD1FOLH1TLR2 | |
| SCHEMBL4587768 | 0.77 | NOD1 (0.39) | NOD1FOLH1TLR2 | |
| SCHEMBL4588703 | 0.77 | FOLH1 (0.37) | FOLH1SIRT5 | |
| SCHEMBL4587729 | 0.75 | NOD1 (0.43) | NOD1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | NITROMED, INC. (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287407-A1 | Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use | PC, PDK1, NOS3 | NOD1 767/4885FOLH1 2571/4885SIRT5 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.