Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354606 | 1.00 | HSP90AA1 (0.52) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL31345827 | 0.86 | L3MBTL1 (0.50) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL29426015 | 0.86 | HSP90AA1 (0.65) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL29426201 | 0.84 | HSP90AA1 (0.55) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL3202619 | 0.83 | HSP90AA1 (0.50) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL422473 | 0.82 | L3MBTL1 (0.56) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL30854808 | 0.82 | L3MBTL1 (0.56) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL9056347 | 0.81 | L3MBTL1 (0.46) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL29409790 | 0.81 | L3MBTL1 (0.46) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL15452179 | 0.79 | L3MBTL1 (0.52) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111467361-B | Application of iridoid glycoside compound in preparation of beta-glucuronidase inhibitor | 浙江工业大学 | 2021-10-15 | — | — | CN | claimed |
| CN-110693893-A | Rehmannia glutinosa extract as therapeutic agent for multiple sclerosis | 香港大学 | 2020-01-17 | — | — | CN | claimed |
| CN-103127296-A | Traditional Chinese medicine composition with lung cancer chemotherapeutic effect-enhancing and toxicity-reducing functions as well as preparation method and application thereof | JIANGSU PROVINCIAL ACADEMY TRADITIONAL CHINESE MEDICINE | 2013-06-05 | — | — | CN | claimed |
| CN-110693893-B | Extracts from rehmannia glutinosa as therapeutic agents for multiple sclerosis | 香港大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114787851-A | Customized cosmetic providing system | 株式会社LG生活健康 | 2022-07-22 | — | — | CN | disclosed |
| CN-113480581-B | Method for extracting iridoid glycoside from rehmannia | 湖南朗林生物资源股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114470094-A | Traditional Chinese medicine composition for promoting mesenchymal stem cells to resist hepatic fibrosis and preparation method thereof | 首都医科大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114306325-A | Traditional Chinese medicine composition for treating hysteromyoma, preparation method and application | 金华宝药王生物工程有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113368185-A | Preparation process and quality control method of lily and rehmannia soup substance standard | 陕西省中医药研究院 | 2021-09-10 | — | — | CN | disclosed |
| EP-3328498-B1 | MEDICAL KIT COMPRISING HERBAL COMBINATIONS FOR TREATING PSORIASIS | SIRBAL LTD (CY) | 2021-05-05 | — | — | EP | disclosed |
| CN-109568496-B | Detection method of traditional Chinese medicine composition for treating diabetes | 陈浩 | 2021-03-30 | — | — | CN | disclosed |
| EP-1437128-B1 | Composition or Kit from pellets for the preparation of medical Chinese tee and its method of preparation | KAUFMANN MICHAEL (DE) | 2008-07-09 | — | — | EP | disclosed |
| CN-1840185-A | Brain-caring compound tablet, its preparation process and quality control method | ANHUI AN TECH MEDICAL AND BIOL (CN) | 2006-10-04 | — | — | CN | disclosed |
| US-20050181080-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2005-08-18 | — | — | US | disclosed |
| EP-1437128-A1 | Pellet made from a matrix comprising tee as starting material and its method of preparation | Kaufmann, Michael (DE) | 2004-07-14 | — | — | EP | disclosed |
| CN-1148206-C | Method for preparing fres rehmannia root preparation | 中国中医研究院中药研究所 | 2004-05-05 | — | — | CN | disclosed |
| US-20030165533-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-09-04 | — | — | US | disclosed |
| US-20030152588-A1 | Chinese traditional medicines for psoriasis | HUANG HSU-SHAN (TW) | 2003-08-14 | — | — | US | disclosed |
| CN-1364469-A | Method for preparing fres rehmannia root preparation | CHINESE PHARMACOLOGY INST CHIN (CN) | 2002-08-21 | — | — | CN | disclosed |
| WO-1996010408-A1 | CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS | THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) | 1996-04-11 | — | — | WO | disclosed |