Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426201 | 0.91 | HSP90AA1 (0.55) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL4604126 | 0.86 | HSP90AA1 (0.52) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL29354606 | 0.86 | HSP90AA1 (0.52) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL31345827 | 0.82 | L3MBTL1 (0.50) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL3202619 | 0.78 | HSP90AA1 (0.50) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL422473 | 0.78 | L3MBTL1 (0.56) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL10307818 | 0.78 | L3MBTL1 (0.53) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL30854808 | 0.78 | L3MBTL1 (0.56) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| Catalpol SCHEMBL420515 | 0.77 | HSP90AA1 (0.65) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 | |
| SCHEMBL29425844 | 0.77 | HSP90AA1 (0.48) | HSP90AA1L3MBTL1XDHPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3409766-B1 | AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS | N ZYME BIOTEC GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |