Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.52 |
| ▸ | LPL | P06858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502667 | 0.86 | LIPG (0.52) | LIPGLPLKMT2AMEN1RIPK1 | |
| SCHEMBL21437973 | 0.85 | LIPG (0.51) | LIPGLPLKMT2AMEN1P4HB | |
| SCHEMBL1684669 | 0.84 | LIPG (0.53) | LIPGLPLNPC1RAB9ACA12 | |
| SCHEMBL15929315 | 0.84 | LIPG (0.45) | LIPGLPLKMT2AMEN1NPC1 | |
| SCHEMBL23607748 | 0.83 | LIPG (0.49) | LIPGLPLKMT2AMEN1NPC1 | |
| SCHEMBL1749553 | 0.83 | LIPG (0.46) | LIPGLPLAOC3RIPK1 | |
| SCHEMBL29888970 | 0.83 | LIPG (0.60) | LIPGLPLALDH1A1 | |
| SCHEMBL2587679 | 0.83 | LIPG (0.60) | LIPGLPLALDH1A1 | |
| Hydrochloric Acid SCHEMBL2006790 | 0.81 | LIPG (0.58) | LIPGLPLHPGDALDH1A1 | |
| SCHEMBL15929475 | 0.81 | LIPG (0.44) | LIPGLPLKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017220431-A1 | FUSED PYRAZOLE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2017-12-28 | — | — | WO | disclosed |
| EP-3022182-A1 | AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009977-A1 | AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |
| EP-1781274-B1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE RECEPTORS OF PPAR TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-11-05 | — | — | EP | disclosed |
| EP-1943213-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | Galderma Research & Development (FR) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007049158-A2 | PPAR MODULATING BIAROMATIC COMPOUNDS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-05-03 | — | — | WO | disclosed |