Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.44 |
| ▸ | LPL | P06858 | 4/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604189 | 0.81 | LIPG (0.52) | LIPGLPLP4HBMEN1KMT2A | |
| SCHEMBL2522095 | 0.81 | UCHL1 (0.31) | — | |
| SCHEMBL12502667 | 0.78 | LIPG (0.52) | LIPGLPLP4HBROCK1MEN1 | |
| SCHEMBL21437973 | 0.77 | LIPG (0.51) | LIPGLPLP4HBROCK1MEN1 | |
| SCHEMBL23607748 | 0.75 | LIPG (0.49) | LIPGLPLP4HBROCK1MEN1 | |
| SCHEMBL29888970 | 0.75 | LIPG (0.60) | LIPGLPLF11 | |
| SCHEMBL2587679 | 0.75 | LIPG (0.60) | LIPGLPLF11 | |
| SCHEMBL12650216 | 0.75 | LIPG (0.60) | LIPGLPLP4HBROCK1F11 | |
| Hydrochloric Acid SCHEMBL2006790 | 0.74 | LIPG (0.58) | LIPGLPLF11 | |
| SCHEMBL108008 | 0.73 | LIPG (0.57) | LIPGLPLP4HBROCK1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802679-B2 | Glycine compound | ASTELLAS PHARMA INC. (JP) | 2014-08-12 | — | — | US | disclosed |