Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 9/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 9/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604232 | 0.87 | KDM4E (0.52) | KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL5555427 | 0.78 | PRKAG1 (0.46) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL4605493 | 0.78 | CHRNA7 (0.60) | KDM4ESMN1; SMN2 | |
| SCHEMBL22915231 | 0.76 | EIF4A3 (0.51) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL4602566 | 0.74 | KDM4E (0.53) | KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL12393388 | 0.74 | PRKAG1 (0.46) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL5430901 | 0.73 | PRKAG1 (0.52) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL176882 | 0.70 | PRKAG1 (0.66) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL16534080 | 0.70 | KDM4E (0.47) | PRKAG1PRKAA1PRKAB1KDM4ESMN1; SMN2 | |
| SCHEMBL27757354 | 0.69 | PRKAG1 (0.43) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940833-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007038367-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, PYRAZOLOPYRIDINES, ISOTHIAZOLOPYRIDINES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |