SCHEMBL4604272

SCHEMBL4604272

[SiH3]O[SiH2]OCCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
IDO1 P14902 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 3/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7509865 0.78 TSHR (0.48) CA1CA2CA9IDO1RAB9A
SCHEMBL7794352 0.78 TAAR1 (0.42) CA1CA2CA9IDO1NPC1
SCHEMBL28729766 0.78 NPC1 (0.43) CA1CA2CA9IDO1NPC1
SCHEMBL523683 0.75 CA1 (0.48) CA1CA2CA9IDO1NPC1
SCHEMBL8502520 0.74 TDP1 (0.36) CA1CA2CA9IDO1NPC1
SCHEMBL704523 0.74 CA1 (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL4195245 0.74 CA1 (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL29162909 0.74 CA1 (0.48) CA1CA2CA9IDO1NPC1
SCHEMBL5666722 0.73 TAAR1 (0.47) CA1CA2CA9IDO1NPC1
SCHEMBL8440988 0.73 KCNH2 (0.37) CA1CA2CA9IDO1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US claimed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US claimed
EP-1249470-A2 Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings Degussa AG (DE) 2002-10-16 EP claimed
EP-1747899-B1 Double-layer infrared-sensitive imageable elements with polysiloxane toplayer EASTMAN KODAK CO (US) 2008-07-16 EP disclosed
EP-1747900-B1 IR-sensitive positive working lithographic printing plate precursor EASTMAN KODAK CO (US) 2008-07-02 EP disclosed
EP-1747899-A1 Double-layer infrared-sensitive imageable elements with polysiloxane toplayer EASTMAN KODAK COMPANY (US) 2007-01-31 EP disclosed
EP-1747900-A1 IR-sensitive positive working lithographic printing plate precursor EASTMAN KODAK COMPANY (US) 2007-01-31 EP disclosed
US-6830816-B2 For preparing lacquer DEGUSSA AG (DE) 2004-12-14 US disclosed
US-20030008974-A1 Highly filled, pasty, composition containing silicoorganic nanohybrid and/or microhybrid capsules for scratch-resistant and/or abrasion-resistant coatings DEGUSSA AG (DE) 2003-01-09 US disclosed
US-4017528-A HYDROLYTIC POLYCONDENSATION OF TETRAALKOXYSILANES OR POLYALKOXYSILOXANES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-04-12 US disclosed