SCHEMBL704523

SCHEMBL704523

C[SiH2]OCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
IDO1 P14902 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705170 0.87 IDO1 (0.55) IDO1AOC3
SCHEMBL703011 0.85 IDO1 (0.48) IDO1TDP1
SCHEMBL28670784 0.85 MEN1 (0.41) CA1CA2CA9IDO1RAB9A
SCHEMBL705288 0.78 CA1 (0.41) CA1CA2CA9IDO1NPC1
SCHEMBL4195245 0.77 CA1 (0.44) CA1CA2CA9IDO1NPC1
SCHEMBL29162909 0.77 CA1 (0.48) CA1CA2CA9IDO1NPC1
SCHEMBL5666722 0.77 TAAR1 (0.47) CA1CA2CA9IDO1NPC1
SCHEMBL28675124 0.77 TSHR (0.54) CA1CA2CA9IDO1ALDH1A1
SCHEMBL713135 0.77 CA1 (0.40) CA1CA2CA9IDO1NPC1
SCHEMBL7794352 0.77 TAAR1 (0.42) CA1CA2CA9IDO1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-110709437-B Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded article 三菱化学株式会社 2022-07-05 CN disclosed
CN-109716544-B Sealing material composition for LED 日产化学株式会社 2021-11-09 CN disclosed
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed
EP-3133105-B1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE SHINETSU CHEMICAL CO (JP) 2020-12-09 EP disclosed
CN-110709437-A Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded article 三菱化学株式会社 2020-01-17 CN disclosed
US-9890251-B2 Hydrosilyl-containing organopolysiloxane, making method, addition curable silicone composition, and semiconductor package SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-13 US disclosed
EP-3133105-A1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-22 EP disclosed
US-20170029571-A1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-02 US disclosed
US-20100179283-A1 SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT ADEKA CORPORATION (JP) 2010-07-15 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
EP-2141188-A1 SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT Adeka Corporation (JP) 2010-01-06 EP disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
EP-0885895-B1 N-[omega-(methyl),omega-(silyl)]alkyl-N-organocarboxamide, their oligomers and polycondensates, process for their preparation and their use DEGUSSA (DE) 2001-11-07 EP disclosed
US-6020448-A N-[ω-(methyl),ω-(silyl)] alkyl-N-organocarboxamides, oligomeric and polycondensed Si-containing compounds thereof, processes for their preparation, and their use HUELS AKTIENGESELLSCHAFT (DE) 2000-02-01 US disclosed
EP-0885895-A2 N-[omega-(methyl),omega-(silyl)]alkyl-N-organocarboxamide, their oligomers and polycondensates, process for their preparation and their use HÜLS AKTIENGESELLSCHAFT (DE) 1998-12-23 EP disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179283-A1 SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT H1-0, H1-10, H1-2 CA1 171/4885CA2 1695/4885CA9 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.