Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | RAF1 | P04049 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307787 | 1.00 | VCAM1 (0.81) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL4605109 | 0.90 | VCAM1 (0.62) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL1258621 | 0.90 | VCAM1 (1.00) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL332714 | 0.89 | VCAM1 (0.63) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL8626465 | 0.89 | TTR (0.62) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL8625340 | 0.89 | VCAM1 (0.96) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL9524519 | 0.88 | VCAM1 (0.81) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL10383201 | 0.87 | VCAM1 (0.87) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL1467263 | 0.85 | VCAM1 (0.68) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL25962653 | 0.85 | VCAM1 (0.90) | VCAM1MAPTALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895991-B1 | Halogenating agent | MITSUI CHEMICALS INC (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-6632949-B2 | Difluoro-diamine methylene derivatives | MITSUI CHEMICALS, INC. (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20030004348-A1 | Halogenating agents | SONODA HIROSHI (JP) | 2003-01-02 | — | — | US | disclosed |
| US-6458990-B1 | BIS(DIHYDROCARBYLAMINO)DIFLUOROMETHANE OR CYCLIC DERIVATIVES THEREOF; FORMING BY REACTING ALKALI METAL HALIDE WITH THE CORRESPONDING AMIDINIUM SALT; FLUORINATION OF ALCOHOLS, THIOPHENOLS, ALDEHYDES, AND KETONES | MITSUI CHEMICALS, INC. (JP) | 2002-10-01 | — | — | US | disclosed |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | SONODA HIROSHI (JP) | 2002-04-11 | — | — | US | disclosed |
| US-6329529-B1 | FOR FLUORINATING OF ORGANIC COMPOUNDS, EFFICIENCY, POLLUTION CONTROL | MITSUI CHEMICALS, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0895991-A2 | Halogenating agent | Mitsui Chemicals, Inc. (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-4556738-A | CATALYTICALLY REDUCING AND DEHALOGENATING A DINITROBENZOPHENONE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004348-A1 | Halogenating agents | AFF1, NAF1, AFF2 | VCAM1 3810/4885MAPT 4532/4885ALDH1A1 833/4885 |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | AFF1, NAF1, CYP2F1 | VCAM1 4109/4885MAPT 4526/4885ALDH1A1 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.