Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | RAF1 | P04049 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604303 | 1.00 | VCAM1 (0.81) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL4605109 | 0.90 | VCAM1 (0.62) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL1258621 | 0.90 | VCAM1 (1.00) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL332714 | 0.89 | VCAM1 (0.63) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL8626465 | 0.89 | TTR (0.62) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL8625340 | 0.89 | VCAM1 (0.96) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL9524519 | 0.88 | VCAM1 (0.81) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL10383201 | 0.87 | VCAM1 (0.87) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL1467263 | 0.85 | VCAM1 (0.68) | VCAM1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL25962653 | 0.85 | VCAM1 (0.90) | VCAM1MAPTALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372986-A | Heat resistant layer containing a polyether | AGFA-GEVAERT, N.V. (BE) | 1994-12-13 | — | — | US | disclosed |
| US-4964890-A | GAS-PERMEABLE FILMS OF A THERMOPLASTIC POLYETHER HAVING DIHYDROXYBENZOPHENONE AND DIHYDROXYDIPHENYLCYCLOALKANE UNITS; DIMENSIONAL STABILITY; HEAT RESISTANCE; MEMBRANES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |