SCHEMBL4604305

SCHEMBL4604305

CCCCCCCCOc1cc(Br)c(OC)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.49
PTPN1 P18031 2/20 0.45
THRA P10827 3/20 0.45
THRB P10828 3/20 0.45
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR2A P28223 3/20 0.43
HTR2C P28335 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.42
S1PR2 O95136 2/20 0.41
S1PR1 P21453 2/20 0.41
S1PR3 Q99500 2/20 0.41
LPAR2 Q9HBW0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2049161 0.92 THRA (0.49) SMPD1THRATHRBMAPTSMN1; SMN2
SCHEMBL339687 0.92 THRA (0.49) SMPD1THRATHRBMAPTSMN1; SMN2
SCHEMBL197292 0.92 THRA (0.49) SMPD1THRATHRBMAPTSMN1; SMN2
SCHEMBL2053781 0.92 THRA (0.49) SMPD1THRATHRBMAPTSMN1; SMN2
SCHEMBL339836 0.92 THRA (0.49) SMPD1THRATHRBMAPTSMN1; SMN2
SCHEMBL2038965 0.90 THRA (0.47) SMPD1THRATHRBMAPTHPGD
SCHEMBL8974077 0.88 SMPD1 (0.49) SMPD1PTPN1THRATHRBMAPT
SCHEMBL25340169 0.86 THRA (0.48) SMPD1PTPN1THRATHRBMAPT
SCHEMBL3854108 0.85 THRA (0.48) SMPD1THRATHRBHPGDSMN1; SMN2
SCHEMBL3858144 0.85 THRA (0.48) SMPD1THRATHRBHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1229063-B2 Polymeric fluorescent substance production thereof and polymer light-emitting device SUMITOMO CHEMICAL CO (JP) 2013-02-13 EP disclosed
EP-1229063-B1 Polymeric fluorescent substance production thereof and polymer light-emitting device SUMITOMO CHEMICAL CO (JP) 2008-07-09 EP disclosed
US-6905785-B2 Polymeric fluorescent substance, production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-06-14 US disclosed
US-20020177687-A1 Polymeric fluorescent substance, production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED 2002-11-28 US disclosed
EP-1229063-A2 Polymeric fluorescent substance production thereof and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-07 EP disclosed