SCHEMBL460468

SCHEMBL460468

Cc1ccc(CN=C=O)cc1CN=C=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.35
TRPA1 O75762 1/20 0.35
MIF P14174 3/20 0.34
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387408 1.00 CYP3A4 (0.35) CYP3A4TRPA1MIFTSHR
SCHEMBL11159589 0.85 MIF (0.34) CYP3A4TRPA1MIFTSHR
SCHEMBL29533789 0.84 CYP3A4 (0.37) CYP3A4TRPA1MIFTSHR
SCHEMBL1148953 0.84 CYP3A4 (0.37) CYP3A4TRPA1MIFTSHR
SCHEMBL11716213 0.84 MIF (0.36) CYP3A4TRPA1MIFTSHR
SCHEMBL8763993 0.83 MIF (0.51) CYP3A4TRPA1MIF
SCHEMBL459299 0.83 GABRA1 (0.36) CYP3A4MIFTSHR
SCHEMBL29386564 0.83 GABRA1 (0.36) CYP3A4MIFTSHR
SCHEMBL14916725 0.82 TAAR1 (0.47) CYP3A4TRPA1
SCHEMBL21175624 0.79 CYP3A4 (0.31) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4775733-A POLYTHIOURETHANES MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-10-04 US claimed
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures COVESTRO DEUTSCHLAND AG (DE) 2026-02-24 US disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-4640731-A1 ONE-COMPONENT COATING COMPOSITION FOR FOOD CONTAINERS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4640732-A1 ONE-COMPONENT SYSTEM FOR COATINGS Covestro Deutschland AG (DE) 2025-10-29 EP disclosed
EP-4357382-B1 IONICALLY MODIFIED POLYISOCYANATE MIXTURE COVESTRO DEUTSCHLAND AG (DE) 2025-07-23 EP disclosed
WO-2025132168-A1 USE OF A SOLVENT-FREE COMPOSITION COMPRISING EPOXY-FUNCTIONAL OXAZOLIDINONES FOR PRODUCING ADHESIVES, SEALING COMPOUNDS, POTTING COMPOUNDS AND COMPOSITES COVESTRO DEUTSCHLAND AG (DE) 2025-06-26 WO disclosed
EP-4574874-A1 POLYISOCYANATE MIXTURE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
EP-4574864-A1 POLYISOCYANATE MIXTURE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
EP-4574863-A1 POLYISOCYANATE MIXTURE Covestro Deutschland AG (DE) 2025-06-25 EP disclosed
US-5756766-A Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1998-05-26 US disclosed
US-5652321-A Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-29 US disclosed
EP-0713105-A2 Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-05-22 EP disclosed
EP-0390218-B1 Anti-reflection optical element HOYA CORP (JP) 1995-08-09 EP disclosed
US-5306799-A High refractive index plastic lens and composition therefor MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
EP-0586091-A2 High refractive index plastic lens and composition therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-03-09 EP disclosed
US-5181141-A Good mechanical and chemical properties HOYA CORPORATION (JP) 1993-01-19 US disclosed
EP-0390218-A2 Anti-reflection optical element HOYA CORPORATION (JP) 1990-10-03 EP disclosed
US-4775733-A POLYTHIOURETHANES MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-10-04 US disclosed
EP-0235743-A1 High-refractivity plastic lens resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559586-B2 Compositions containing uretdione groups crosslinking at low temperatures URB2, UQCRB, UQCRC2 CYP3A4 1937/4885TRPA1 4523/4885MIF 4002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.