SCHEMBL4604748

SCHEMBL4604748

CCC(OC(=O)C1(C)CC2C=CC1C2)[Si](OC)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.36
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
CETP P11597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603860 0.89 P2RX7 (0.33) P2RX7CYP2D6CYP2C19CETP
SCHEMBL6827829 0.86 P2RX7 (0.34) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5186802 0.80 CYP2D6 (0.36) P2RX7CYP2D6CYP2C19CETP
SCHEMBL1451757 0.80 CYP2D6 (0.36) P2RX7CYP2D6CYP2C19CETP
SCHEMBL3367328 0.77 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP
SCHEMBL5184481 0.77 P2RX7 (0.37) P2RX7CYP2D6CYP2C19CETP
SCHEMBL4602588 0.76 CYP2D6 (0.34) P2RX7CYP2D6CYP2C19CETP
SCHEMBL3364369 0.75 CYP2D6 (0.35) P2RX7CYP2D6CYP2C19CETP
SCHEMBL18938394 0.75 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP
SCHEMBL200115 0.75 P2RX7 (0.41) P2RX7CYP2D6CYP2C19CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20070225461-A1 Olefin polymers for imaging members LEXMARK INTERNATIONAL INC. 2007-09-27 US disclosed
US-20070112158-A1 Novel (co)polymer, process for producing the same, and process for producing carboxylated (co)polymer JSR CORPORATION (JP) 2007-05-17 US disclosed
EP-1686139-A1 NOVEL (CO)POLYMER, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING CARBOXYLATED (CO)POLYMER JSR Corporation (JP) 2006-08-02 EP disclosed
US-6911507-B2 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2005-06-28 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed