Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CREB1 | P16220 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231012 | 0.73 | GAA (0.45) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL4604946 | 0.70 | GAA (0.41) | GAAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL4454649 | 0.67 | GAA (0.46) | GAAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL2612448 | 0.66 | NPSR1 (0.57) | GAANPSR1LMNA | |
| SCHEMBL8488845 | 0.66 | GAA (0.38) | GAAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL3905949 | 0.66 | GAA (0.45) | GAA | |
| SCHEMBL4449574 | 0.66 | GAA (0.42) | GAAALDH1A1 | |
| SCHEMBL1274016 | 0.65 | KDM4E (0.41) | GAAMEN1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL29612322 | 0.65 | MAPT (0.49) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL2035337 | 0.64 | ALDH1A1 (0.39) | GAAMEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934278-A2 | NON-STAINING ANTIDEGRADANTS FOR VULCANIZED ELASTOMERS | Ciba Holding Inc. (CH) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042418-A2 | NON-STAINING ANTIDEGRADANTS FOR VULCANIZED ELASTOMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-19 | — | — | WO | disclosed |
| EP-0892827-A1 | STABILIZER COMPOSITION | Clariant Finance (BVI) Limited (VG) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997039051-A1 | STABILIZER COMPOSITION | CLARIANT FINANCE (BVI) LIMITED (VG) | 1997-10-23 | — | — | WO | disclosed |