Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608225 | 0.82 | SCN9A (0.44) | SLC6A2SLC6A4KDM1AMAOBGPR88 | |
| SCHEMBL4606553 | 0.82 | SLC6A2 (0.61) | SLC6A2SLC6A4NPC1RAB9AKDM1A | |
| SCHEMBL6732081 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4NPC1RAB9AKDM1A | |
| SCHEMBL23982275 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4NPC1RAB9AKDM1A | |
| SCHEMBL6732079 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4NPC1RAB9AKDM1A | |
| SCHEMBL4606990 | 0.79 | ALDH1A1 (0.49) | SLC6A2SLC6A4KDM1AHTR2C | |
| SCHEMBL4604973 | 0.77 | KDM1A (0.61) | NPC1RAB9AKDM1AMAOAMAOB | |
| SCHEMBL4607726 | 0.77 | HRH3 (0.46) | SLC6A2SLC6A4KDM1AMAOAMAOB | |
| SCHEMBL4607106 | 0.77 | SLC6A4 (0.43) | SLC6A2SLC6A4KDM1APARP1 | |
| SCHEMBL4608244 | 0.77 | SIRT2 (0.40) | SLC6A2SLC6A4RAB9AGAAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |