Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamidine SCHEMBL27905134 | 0.87 | PARP1 (0.53) | PARP1NPC1RAB9AKMT2APOLB | |
| SCHEMBL1064314 | 0.85 | ATM (0.46) | PARP1SMN1; SMN2PKMCYP1A2GAA | |
| SCHEMBL29397067 | 0.83 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL4188727 | 0.83 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL44313 | 0.83 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL31316346 | 0.83 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL40429 | 0.82 | GPR17 (0.65) | PARP1HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL669300 | 0.82 | PARP1 (0.64) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL29534771 | 0.82 | GPR17 (0.65) | PARP1HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL6904430 | 0.82 | PARP1 (0.59) | PARP1HDAC8HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221224708-U | Ammonia toluic acid sample impurity detection device | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-221208086-U | Hydrogenated liquid conversion kettle for producing aminomethylbenzoic acid | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-112457209-A | Improved synthesis process of 2-amino-5-chloro-N, 3-dimethylbenzamide | 江苏优普生物化学科技股份有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-102816077-A | Application of urotropine as catalyst in aminomethylbenzoic acid synthesis | SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD | 2012-12-12 | — | — | CN | claimed |
| CN-221224708-U | Ammonia toluic acid sample impurity detection device | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-221224708-U | Ammonia toluic acid sample impurity detection device | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-221224708-U | Ammonia toluic acid sample impurity detection device | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-221208086-U | Hydrogenated liquid conversion kettle for producing aminomethylbenzoic acid | 云南衡楚药业有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-116730856-B | Synthesis method of tranexamic acid | 浙江竹子制药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117310057-A | High performance liquid chromatography detection method for aminomethylbenzoic acid related substances | 天和药业股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116730856-A | Synthesis method of tranexamic acid | 浙江竹子制药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-114436873-B | Preparation method of tranexamic acid | 上海巽田科技股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013074518-A1 | MODULATING CERTAIN TYROSINE KINASES | TESARO, INC. (US) | 2013-05-23 | — | — | WO | disclosed |
| CN-102816077-A | Application of urotropine as catalyst in aminomethylbenzoic acid synthesis | SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD | 2012-12-12 | — | — | CN | disclosed |
| CN-102718673-A | Novel technology for synthesis of aminomethylbenzoic acid | JIANG CHANG | 2012-10-10 | — | — | CN | disclosed |
| CN-201264979-Y | Manufacturing system of material layer and manufacturing system of polaroid | DAXON TECHNOLOGY INC (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-101287702-A | N-phenyl phenylacetamide non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-10-15 | — | — | CN | disclosed |
| EP-1940782-A1 | N-PHENYL PHENYLACETAMIDE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INIHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045572-A1 | N-PHENYL PHENYLACETAMIDE NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INIHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-04-26 | — | — | WO | disclosed |