Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31316346 | 0.85 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL44313 | 0.85 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL29397067 | 0.85 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL4188727 | 0.85 | PARP1 (0.61) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL2064872 | 0.84 | PARP1 (0.55) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL40429 | 0.83 | GPR17 (0.65) | PARP1HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL29534771 | 0.83 | GPR17 (0.65) | PARP1HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL669300 | 0.83 | PARP1 (0.64) | PARP1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL28289702 | 0.83 | GPR17 (0.65) | PARP1HDAC8HDAC6RAB9AKMT2A | |
| SCHEMBL4605445 | 0.82 | PARP1 (0.62) | PARP1HDAC8HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448683-A2 | PROCESS OF PRODUCING EXPANDED POLYPROPYLENE RESIN BEADS | JSP Corporation (JP) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003037971-A2 | PROCESS OF PRODUCING EXPANDED POLYPROPYLENE RESIN BEADS | JSP CORPORATION (JP) | 2003-05-08 | — | — | WO | disclosed |