Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624437 | 0.81 | KDM4E (0.56) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL4149713 | 0.80 | KDM4E (0.51) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL4603440 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL13696992 | 0.79 | HSD17B10 (0.50) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL13696902 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL17066136 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL4163106 | 0.75 | KDM4E (0.53) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL13696899 | 0.75 | HIF1A (0.49) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| Aminacrine SCHEMBL29566014 | 0.72 | HSD17B10 (0.75) | ALDH1A1HSD17B10KDM4EHPGDACHE | |
| SCHEMBL4162331 | 0.72 | RAB9A (0.43) | ALDH1A1HSD17B10KDM4EHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| EP-1940965-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI Scotland Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |