Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606618 | 1.00 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL733703 | 0.96 | KMT2A (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| Cysteine SCHEMBL19971581 | 0.92 | KDM4E (0.61) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL28531880 | 0.81 | KMT2A (0.86) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL31373413 | 0.78 | MAPT (0.76) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL1839783 | 0.78 | KMT2A (0.80) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL1839782 | 0.78 | KMT2A (0.80) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL28267454 | 0.78 | KMT2A (0.97) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL11064226 | 0.78 | KMT2A (0.97) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL23141133 | 0.76 | KMT2A (1.00) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068339-B1 | COMPOSITIONS AND METHODS FOR PROTEIN SECRETION | UNIV ALBERTA (CA) | 2008-07-23 | — | — | EP | claimed |
| EP-1068339-B1 | COMPOSITIONS AND METHODS FOR PROTEIN SECRETION | UNIV ALBERTA (CA) | 2008-07-23 | — | — | EP | disclosed |