Cysteine

Cysteine

SCHEMBL19971581

NC(CS)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)C1=CC(=O)C=CC1=O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.61
▸ MAPT P10636 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ LMNA P02545 2/20 0.61
▸ TSHR P16473 2/20 0.61
▸ BLM P54132 2/20 0.61
▸ PMP22 Q01453 2/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ MPO P05164 1/20 0.61
▸ HIF1A Q16665 1/20 0.61
▸ DNMT1 P26358 3/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ APAF1 O14727 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ACE P12821 1/20 0.45
▸ ECE1 P42892 3/20 0.45
▸ ALDH1A1 P00352 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL733703 0.94 KMT2A (0.70) KDM4EMAPTKMT2ALMNATSHR
SCHEMBL4606618 0.92 KDM4E (0.61) KDM4EMAPTKMT2ALMNATSHR
SCHEMBL4606621 0.92 KDM4E (0.61) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL28523647 0.87 KMT2A (0.76) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL626285 0.84 KDM4E (0.86) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL9486225 0.84 KDM4E (0.86) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL8406412 0.84 KDM4E (0.86) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27152251 0.84 KDM4E (0.86) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28650342 0.83 KDM4E (0.84) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27984227 0.83 KDM4E (0.84) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ERBER AKTIENGESELLSCHAFT (AT) 2021-05-11 — — US claimed
EP-4022047-B1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL DSM Austria GmbH (AT) 2026-04-22 — — EP disclosed
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 — — EP disclosed
US-20260062700-A1 ENGINEERED RETRONS AND METHODS OF USE RENAGADE THERAPEUTICS MAN INC (US) 2026-03-05 — — US disclosed
US-20250340901-A1 GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE RENAGADE THERAPEUTICS MAN INC (US) 2025-11-06 — — US disclosed
EP-3273802-B1 USE OF A TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE DSM Austria GmbH (AT) 2025-06-25 — — EP disclosed
WO-2025049959-A9 GENE EDITING SYSTEMS, COMPOSITIONS, AND METHODS FOR TREATMENT OF VEXAS SYNDROME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-06-12 — — WO disclosed
EP-4558624-A2 GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE Renagade Therapeutics Management Inc. (US) 2025-05-28 — — EP disclosed
US-12264328-B2 Gene editing components, systems, and methods of use ReNAgade Therapeutics Management, Inc. (US) 2025-04-01 — — US disclosed
WO-2025049959-A2 GENE EDITING SYSTEMS, COMPOSITIONS, AND METHODS FOR TREATMENT OF VEXAS SYNDROME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-03-06 — — WO disclosed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 — — WO disclosed
US-20230011323-A1 REACTOR SYSTEM AND METHODS FOR USING THEREOF PHOENIX BIOSCIENCES SA (BE) 2023-01-12 — — US disclosed
WO-2023275355-A1 REACTOR SYSTEM AND METHODS FOR USING THEREOF QUANTOOM BIOSCIENCES S.A. (BE) 2023-01-05 — — WO disclosed
US-20220372450-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL DSM Austria GmbH (AT) 2022-11-24 — — US disclosed
EP-4022047-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL Erber Aktiengesellschaft (AT) 2022-07-06 — — EP disclosed
WO-2021252975-A2 SPLIT INTEIN-BASED SELECTION FOR PEPTIDE BINDERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-12-16 — — WO disclosed
WO-2021249980-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI-DEOXYNIVALENOL ERBER AKTIENGESELLSCHAFT (AT) 2021-12-16 — — WO disclosed
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ERBER AKTIENGESELLSCHAFT (AT) 2021-05-11 — — US disclosed
WO-2021038026-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL ERBER AKTIENGESELLSCHAFT (AT) 2021-03-04 — — WO disclosed
US-20180080011-A1 TRICHOTHECENE-TRANSFORMING ALCOHOL DEHYDROGENASE, METHOD FOR TRANSFORMING TRICHOTHECENES AND TRICHOTHECENE-TRANSFORMING ADDITIVE ERBER AKTIENGESELLSCHAFT (AT) 2018-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062700-A1 ENGINEERED RETRONS AND METHODS OF USE NSUN3, RNASEH1, TRMT1L KDM4E 3299/4885MAPT 3662/4885KMT2A 1681/4885
US-20220372450-A1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL VIP, PREP, NGLY1 KDM4E 2065/4885MAPT 4807/4885KMT2A 3042/4885
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ADH5, IDH3A, ADH4 KDM4E 2762/4885MAPT 2999/4885KMT2A 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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