Dl-Tryptophan

Dl-Tryptophan

SCHEMBL733703

NC(Cc1c[nH]c2ccccc12)C(=O)C1=CC(=O)C=CC1=O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.70
▸ KDM4E B2RXH2 3/20 0.70
▸ MAPT P10636 3/20 0.70
▸ LMNA P02545 2/20 0.70
▸ TSHR P16473 2/20 0.70
▸ BLM P54132 2/20 0.70
▸ PMP22 Q01453 2/20 0.70
▸ MEN1 O00255 2/20 0.70
▸ MPO P05164 1/20 0.70
▸ HIF1A Q16665 1/20 0.70
▸ DNMT1 P26358 3/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ HTR1A P08908 2/20 0.50
▸ HTR2A P28223 2/20 0.50
▸ HTR2C P28335 2/20 0.50
▸ SLC6A4 P31645 2/20 0.50
▸ HTR7 P34969 2/20 0.50
▸ HTR2B P41595 2/20 0.50
▸ POLB P06746 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4606618 0.96 KDM4E (0.61) KMT2AKDM4EMAPTLMNATSHR
SCHEMBL4606621 0.96 KDM4E (0.61) KMT2AKDM4EMAPTLMNATSHR
Cysteine SCHEMBL19971581 0.94 KDM4E (0.61) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL28531880 0.87 KMT2A (0.86) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL28267454 0.85 KMT2A (0.97) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL11064226 0.85 KMT2A (0.97) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL1839783 0.84 KMT2A (0.80) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL1839782 0.84 KMT2A (0.80) KMT2AKDM4EMAPTLMNATSHR
Tryptophan SCHEMBL23141133 0.83 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR
Dl-Tryptophan SCHEMBL7327 0.83 KMT2A (1.00) KMT2AKDM4EMAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644559-A1 METHOD FOR ENZYME-ASSISTED PLASMA CHEMICAL REACTION Leibniz-Institut für Plasmaforschung und Technologie e.V. (DE) 2025-11-05 — — EP claimed
US-20240310288-A1 TETRAZOLIUM-BASED COLORIMETRIC ASSAY UNIVERSITY OF SOUTH CAROLINA 2024-09-19 — — US claimed
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ERBER AKTIENGESELLSCHAFT (AT) 2021-05-11 — — US claimed
US-10745589-B2 Chemical mechanical polishing (CMP) of cobalt-containing substrate VERSUM MATERIALS US, LLC (US) 2020-08-18 — — US claimed
US-20190172720-A1 Chemical Mechanical Polishing (CMP) of Cobalt-Containing Substrate VERSUM MATERIALS US, LLC (US) 2019-06-06 — — US claimed
EP-3257910-B1 CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION, METHOD AND SYSTEM FOR COBALT-CONTAINING SUBSTRATE VERSUM MAT US LLC (US) 2019-03-27 — — EP claimed
US-20170362466-A1 Chemical Mechanical Polishing (CMP) of Cobalt-Containing substrate VERSUM MATERIALS US, LLC (US) 2017-12-21 — — US claimed
EP-3257910-A1 CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION, METHOD AND SYSTEM FOR COBALT-CONTAINING SUBSTRATE Versum Materials US, LLC (US) 2017-12-20 — — EP claimed
US-20160027657-A1 Chemical Mechanical Polishing (CMP) of Colbalt-Containing Substrate AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-28 — — US claimed
EP-2977418-A1 CHEMICAL MECHANICAL POLISHING (CMP) OF COBALT-CONTAINING SUBSTRATE AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-27 — — EP claimed
US-20030064435-A1 Compositions and methods for protein secretion WEINER JOEL HIRSCH (CA) 2003-04-03 — — US claimed
US-6335178-B1 RECOMBINANT PRODUCTION OF SOLUBLE PROTEINS BY LINKING NUCLEOTIDE SEQUENCE OF INTEREST TO SEQUENCE ENCODING TWIN-ARGININE SIGNAL AMINO ACID SEQUENCE, THEN TRANSFORMING HOST CELL AND ALLOWING GENE EXPRESSION UNIVERSITY OF ALBERTA (CA) 2002-01-01 — — US claimed
EP-1068339-A1 COMPOSITIONS AND METHODS FOR PROTEIN SECRETION The Governors of the University of Alberta (CA) 2001-01-17 — — EP claimed
WO-1999051753-A1 COMPOSITIONS AND METHODS FOR PROTEIN SECRETION THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 1999-10-14 — — WO claimed
EP-4743437-A1 DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-05-20 — — EP disclosed
EP-4731258-A1 LIPID NANOPARTICLES CONTAINING DISULFIDE LIPIDS AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-04-29 — — EP disclosed
EP-4022047-B1 IMPROVED POLYPEPTIDES CAPABLE OF CONVERTING SUBSTRATE 3-KETO- DEOXYNIVALENOL INTO 3-EPI- DEOXYNIVALENOL DSM Austria GmbH (AT) 2026-04-22 — — EP disclosed
EP-0960192-A1 SYNTHETIC POLYNUCLEOTIDES THE UNIVERSITY OF SYDNEY (AU) 1999-12-01 — — EP disclosed
WO-1999051753-A1 COMPOSITIONS AND METHODS FOR PROTEIN SECRETION THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 1999-10-14 — — WO disclosed
WO-1998006830-A1 SYNTHETIC POLYNUCLEOTIDES THE UNIVERSITY OF SYDNEY (AU) 1998-02-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001812-B2 Trichothecene-transforming alcohol dehydrogenase, method for transforming trichothecenes and trichothecene-transforming additive ADH5, IDH3A, ADH4 KMT2A 933/4885KDM4E 2762/4885MAPT 2999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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