Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.71 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605918 | 0.85 | GRIA2 (0.73) | GRIA4GRIA2KCNH2 | |
| SCHEMBL14141327 | 0.85 | GRIA2 (0.73) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607295 | 0.85 | GRIA2 (0.73) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607332 | 0.83 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL6761009 | 0.83 | GRIA4 (0.62) | GRIA4GRIA2KCNH2 | |
| SCHEMBL6761007 | 0.83 | GRIA4 (0.62) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4608724 | 0.82 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607609 | 0.82 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 | |
| SCHEMBL4607921 | 0.82 | GRIA4 (0.77) | GRIA4GRIA2KCNH2 | |
| SCHEMBL6554606 | 0.82 | GRIA4 (1.00) | GRIA4GRIA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |