Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27850055 | 0.93 | KDM4E (0.82) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL4820784 | 0.93 | — | — | |
| SCHEMBL11300 | 0.93 | — | — | |
| SCHEMBL25262333 | 0.93 | KDM4E (0.90) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL13758294 | 0.93 | KDM4E (0.90) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL14528349 | 0.91 | ALDH1A1 (0.72) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL11200585 | 0.90 | KDM4E (0.95) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| Iodide SCHEMBL14778132 | 0.90 | KDM4E (0.86) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL16604261 | 0.90 | KDM4E (0.95) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL10955826 | 0.90 | KDM4E (0.95) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667987-B1 | PROCESS FOR THE PRODUCTION OF MYCOPHENOLATE MOFETIL | SANDOZ AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-20070032483-A1 | Process for the production of mycophenolate mofetil | SANDOZ AG (CH) | 2007-02-08 | — | — | US | disclosed |
| EP-1667987-A2 | PROCESS FOR THE PRODUCTION OF MYCOPHENOLATE MOFETIL | Sandoz AG (CH) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005023791-A2 | PROCESS FOR THE PRODUCTION OF MYCOPHENOLATE MOFETIL | SANDOZ AG (CH) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032483-A1 | Process for the production of mycophenolate mofetil | TPMT, MTX2, MYC | ALDH1A1 1716/4885KDM4E 600/4885GLA 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.