Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 9/20 | 0.72 |
| ▸ | THRB | P10828 | 8/20 | 0.72 |
| ▸ | THRA | P10827 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087278 | 0.89 | THRB (0.68) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL12921186 | 0.88 | THRB (0.68) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL14264009 | 0.88 | THRB (0.68) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL14292277 | 0.85 | THRB (0.68) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL22103797 | 0.85 | THRB (0.65) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL14264008 | 0.84 | THRB (0.67) | PCNATHRBTHRAPOLBHIF1A | |
| Thyropropic Acid SCHEMBL310201 | 0.84 | PCNA (1.00) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL14230042 | 0.84 | PCNA (0.64) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL281910 | 0.83 | THRB (0.76) | PCNATHRBTHRAPOLBHIF1A | |
| SCHEMBL6825136 | 0.82 | THRB (0.85) | PCNATHRBTHRAPOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831769-B2 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | LAVIN DR THOMAS N (US) | 2008-07-23 | — | — | EP | claimed |