Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.68 |
| ▸ | THRA | P10827 | 7/20 | 0.68 |
| ▸ | PCNA | P12004 | 7/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606819 | 0.88 | PCNA (0.72) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL14264009 | 0.85 | THRB (0.68) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL13886598 | 0.84 | TAAR5 (0.68) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL13886595 | 0.84 | TAAR1 (0.56) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL13886596 | 0.83 | THRB (0.60) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL14292277 | 0.83 | THRB (0.68) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL7087278 | 0.83 | THRB (0.68) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL22103797 | 0.82 | THRB (0.65) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL13886597 | 0.82 | TAAR1 (0.74) | THRBTHRAPCNAPOLBHIF1A | |
| SCHEMBL14264008 | 0.81 | THRB (0.67) | THRBTHRAPCNAPOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260089169-A1 | SYSTEM AND METHOD FOR VERIFYING THE IDENTITY OF EMAIL SENDERS TO IMPROVE EMAIL SECURITY WITHIN AN ORGANIZATION | PAUBOX INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12519804-B2 | System and method for verifying the identity of email senders to improve email security within an organization | Paubox, Inc. (US) | 2026-01-06 | — | — | US | disclosed |
| CN-119598892-A | Transition measurement and correction method based on laminar flow kinetic energy transport equation model | 四川天府流体大数据研究中心 | 2025-03-11 | — | — | CN | disclosed |
| CN-115298573-B | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2024-09-06 | — | — | CN | disclosed |
| US-20240106835-A1 | SYSTEM AND METHOD FOR VERIFYING THE IDENTITY OF EMAIL SENDERS TO IMPROVE EMAIL SECURITY WITHIN AN ORGANIZATION | WESTERN ALLIANCE BANK | 2024-03-28 | — | — | US | disclosed |
| US-20110009351-A1 | SCREENING ASSAY TO IDENTIFY CORRECTORS OF PROTEIN TRAFFICKING DEFECTS | Traffick Therepeutics Inc. | 2011-01-13 | — | — | US | disclosed |
| US-20090105347-A1 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | US | disclosed |
| US-7355079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-08 | — | — | US | disclosed |
| US-7339079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| US-7321065-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105347-A1 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | TPO, TSHR, THRB | THRB 3/4885THRA 4/4885PCNA 4495/4885 |
| US-20260089169-A1 | SYSTEM AND METHOD FOR VERIFYING THE IDENTITY OF EMAIL SENDERS TO IMPROVE EMAIL SECURITY WITHIN AN ORGANIZATION | UBE2M, SET, NEDD8 | THRB 2572/4885THRA 2962/4885PCNA 4773/4885 |
| US-20110009351-A1 | SCREENING ASSAY TO IDENTIFY CORRECTORS OF PROTEIN TRAFFICKING DEFECTS | CLINT1, SLC47A2, GOLT1B | THRB 1924/4885THRA 2671/4885PCNA 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.