Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.42 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.42 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289317 | 0.87 | MAOA (0.42) | KCNN2KCNN3KCNN1MAOALMNA | |
| SCHEMBL10994941 | 0.84 | ABCB1 (0.42) | KCNN2KCNN3KCNN1MAOALMNA | |
| SCHEMBL296779 | 0.83 | MTNR1A (0.40) | HTT | |
| SCHEMBL10993273 | 0.83 | KCNN2 (0.44) | KCNN2KCNN3KCNN1MAOALMNA | |
| Hydrochloric Acid SCHEMBL10993157 | 0.83 | MAOA (0.44) | KCNN2KCNN3KCNN1MAOALMNA | |
| SCHEMBL10993103 | 0.83 | ABCB1 (0.41) | BCHEACHEKCNN2KCNN3KCNN1 | |
| SCHEMBL7291340 | 0.82 | BCHE (0.50) | BCHEACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10990748 | 0.82 | MAOA (0.46) | KCNN2KCNN3KCNN1MAOALMNA | |
| Hydrochloric Acid SCHEMBL10992437 | 0.82 | MAOA (0.43) | BCHEACHEKCNN2KCNN3KCNN1 | |
| SCHEMBL2898321 | 0.80 | HTR2A (0.41) | RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | claimed |
| EP-1946778-A1 | Active substance combination for the treatment of diabetes | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | claimed |
| US-20070073056-A1 | 4-Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-03-29 | — | — | US | claimed |
| US-20060014709-A1 | Drug or cosmetic | ISHIBASHI MICHIO | 2006-01-19 | — | — | US | claimed |
| EP-1541174-A1 | DRUG OR COSMETIC | Ishibashi, Michio (JP) | 2005-06-15 | — | — | EP | claimed |
| EP-1950563-A2 | Method for screening for a substance for promoting regeneration of macrophages | Ishibashi, Michio (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-1950563-A2 | Method for screening for a substance for promoting regeneration of macrophages | Ishibashi, Michio (JP) | 2008-07-30 | — | — | EP | disclosed |
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1946778-A1 | Active substance combination for the treatment of diabetes | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| EP-1917247-A1 | 4,5-DIHYDR0-1H-PYRAZOLE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-07 | — | — | EP | disclosed |
| US-20070073056-A1 | 4-Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-03-29 | — | — | US | disclosed |
| WO-2007009689-A1 | 4,5-DIHYDR0-1H-PYRAZOLE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR.ESTEVE, S.A. (ES) | 2007-01-25 | — | — | WO | disclosed |
| US-20060014709-A1 | Drug or cosmetic | ISHIBASHI MICHIO | 2006-01-19 | — | — | US | disclosed |
| EP-1541174-A1 | DRUG OR COSMETIC | Ishibashi, Michio (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073056-A1 | 4-Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments | P2RX4, PIR, P2RY4 | BCHE 1843/4885ACHE 570/4885KCNN2 935/4885 |
| US-20060014709-A1 | Drug or cosmetic | CTSA, MSR1, CD68 | BCHE 1498/4885ACHE 744/4885KCNN2 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.